(3)Prevents gum disease*3 and protects gum health through a double-action approach
Contains vitamin E (tocopherol acetate), which enhances barrier function. Contains β-glycyrrhetinic acid, which has an anti-inflammatory effect.
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On March 26, 2025, Lion Corporation (President: Masayuki Takemori) will launch nationwide sales of CLINICA PRO plus Periodontal Barrier Toothpaste from its CLINICA PRO line of medicated toothpastes, the only toothpastes in Japan formulated with an enzyme*2 as an active ingredient to break down and remove plaque. Taking a double-action approach, this gum disease*3 prevention toothpaste will keep gums healthy.
*1 Acting as both a barrier-enhancing and anti-inflammatory agent
*2 Dextranase. Based on toothpaste sales (October 2023 Lion survey)
*3 Ginigivitis and periodontitis
The CLINICA brand was created from a preventive dentistry perspective. Under this brand, Lion has been advancing activities to contribute to the uptake and broad practice of preventive dentistry.
A preventive approach is necessary to the proactive protection of oral health and involves both regular professional care at a dentist’s office and daily self-care in line with the guidance of a dentist or dental hygienist. While the quality of both professional care and consumer self-care practices has improved, only 40%*4 or so of consumers receive regular dental checkups at least once a year and about 50%*5 use dental floss in their self-care routines. Currently, 31% of people in their 40s or older have untreated tooth decay and 55%*6 have evidence of periodontal disease.
In response, Lion has launched CLINICA PRO plus Periodontal Barrier Toothpaste in its CLINICA PRO line, which supports the practice of high-quality preventive dentistry. This line is designed to encourage those who are becoming increasingly concerned with the health of not only their teeth but also their gums to make preventive dentistry an everyday habit.
*4 Lion’s own survey (n=1,000, people ages 10 to 69)
*5 “2022 Survey of Dental Diseases” by the Ministry of Health, Labour and Welfare
*6 People with periodontitis (periodontal pockets 4mm or larger)
March 26, 2025, nationwide
| Product name | Volume | Retail price | |
|---|---|---|---|
| CLINICA PRO plus Periodontal Barrier Toothpaste (Quasi drugs) Brand name: CLINICA Wa |
Natural Green Mint | 95g | Open price |
(1) One of the only toothpastes in Japan*2 formulated with an enzyme as an active ingredient to break down and remove plaque, a cause of many oral health issues. Enzymes break down and remove plaque in every nook and cranny that toothbrushes cannot reach.
(2)Fluoride strengthens tooth structure. Prevents tooth decay and keeps teeth healthy. Contains a high concentration of 1,450 ppm of fluoride*7
*7 This product is not recommended for use by children under 6 years of age.
(3)Prevents gum disease*3 and protects gum health through a double-action approach
Contains vitamin E (tocopherol acetate), which enhances barrier function. Contains β-glycyrrhetinic acid, which has an anti-inflammatory effect.
(4)Kills harmful bacteria and prevents bad breath
(5)Refreshing and clean “natural green mint” flavor with an herbal green base
Includes the product this release focuses on
From left, the two flavors of CLINICA PRO All-in-One (Fresh Clean Mint, Rich Citrus Mint) ,
CLINICA PRO plus Whitening and CLINICA PRO plus Periodontal Barrier Toothpaste
| Product name | Volume | |
|---|---|---|
| CLINICA PRO All-in-One (Seven-Risk Care*8) (Quasi drugs) |
Fresh Clean Mint Brand name: CLINICA Xa |
95g |
| Rich Citrus Mint Brand name: CLINICA Xb |
||
| CLINICA PRO plus Whitening* (Quasi drugs) |
Rich Fresh Mint Brand name: CLINICA RAa |
95g |
| CLINICA PRO plus Periodontal Barrier Toothpaste (Quasi drugs) |
Natural Green Mint Brand name: CLINICA Wa |
95g |
*8 Cavities, plaque, gum disease (inflamed gums, gingivitis), hypersensitivity, bad breath, staining, tartar deposition
These are seven oral issues that females aged 10 to 69 want their toothpastes to address (May 2021 Lion survey).
*In conjunction with the launch of this release, the name of CLINICA PRO Whitening Toothpaste will be changed to CLINICA PRO plus Whitening Toothpaste and the packaging will also be changed (effective from March 2025).
CLINICA brand site ( Japanese )
https://clinica.lion.co.jp/