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First new enzyme in NANOX history: With the launch of this renewed version of NANOX one, Lion marks the achievement of gene-level cleaning that gets down to the bacterial root*1

Aug. 05, 2025 Products & Services

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Lion Corporation (Representative Director, President and Executive Officer: Masayuki Takemori) is set to launch the fully renewed version of NANOX one laundry detergent. By adopting a new enzyme for the first time in the brand’s history, the product has been reimagined as a “Super Enzyme Complete Gel” capable of thoroughly cleansing clothing of even bacteria-derived DNA that causes yellowing and odors. It will be newly launched across Japan in September 2025.
*1 Cleaning of bacteria-derived DNA involved in the formation of grime and odors.

  • First new enzyme in NANOX history: With the launch of this renewed version of NANOX one, Lion marks the achievement of gene-level cleaning that gets down to the bacterial root*1
  • A clothing care formula that helps prevent yellowing, darkening, and dullness, while also protecting against color fading for longer-lasting wear.

1. Objective of Introducing the New Product

With its advanced detergency and superior wash finish, NANOX one helps create habits that keep clothes cleaner and wearable for longer.
Through a Company survey, we found that the three leading sources of dissatisfaction regarding residual stains and odors after washing are collar and cuff stains, yellowing, and musty odors from damp laundry.*2 These are problems that ordinary detergents struggle to resolve, leaving many consumers to simply give up on them.
Our research into the causes of such stains and odors revealed that bacteria-derived DNA that was not being fully removed by our existing detergents, plays a role. As a result, stains and odors remain on clothing. Drawing on the results of long-standing enzyme research, we have adopted an enzyme capable of breaking down and removing even bacteria-derived DNA. With this, NANOX one has been renewed and will relaunch as a laundry detergent that thoroughly removes even stubborn yellowing and odors.
*2 n=3,400, Lion web survey conducted in September 2024

2. Release Date and Region

NANOX one For Odors*3 September 10, 2025 (Wed.), Nationwide
NANOX one Washing Plus/NANOX one PRO*3 September 24, 2025 (Wed.), Nationwide
*3 Ultra Jumbo, Mega Jumbo, and One-Pack (NANOX one PRO only) to be gradually switched over in September 2025

3. Product Name, Contents and Price

Product name Contents Recommended Retail price
NANOX one Washing Plus Bottle (large): 600g
Refill packs: 765g / 1,080g / 1,530g
No recommended retail price
For Odors
PRO Bottle (large): 600g
Refill packs: 740g / 1,010g / 1,400g
One-Pack: 10g x 6 bags

4. Product Features

(1) With the first new enzyme in NANOX history, the “Super Enzyme Complete Gel” achieves gene-level cleaning that gets down to the bacterial root,*1 completing eliminating yellowing and odors
Laundry washed with Lion’s existing detergents left bacteria-derived DNA and stains on clothes, which is one of the causes of hard-to-remove yellowing and unpleasant odors.

〈Visualization of washing with existing Lion detergents〉

In contrast, the renewed NANOX one with its newly adopted enzyme enables the breakdown of bacteria-derived DNA—something difficult with the brand’s existing detergents—making it possible to thoroughly eliminate yellowing and odors.

〈Visualization of washing with the new NANOX one featuring the new enzyme〉

[Lion’s history of enzyme research]
For many years, Lion has pursued enzyme research to develop detergents that make everyday laundry easier.
In 1979, we launched TOP with Enzyme Power, the first detergent to incorporate enzymes as components that break down protein stains, dramatically improving detergency. In 1988, we followed with Hi TOP, which incorporated a lipid-degrading enzyme (a high-tech enzyme), further advancing cleaning technologies that utilize enzymes.
With this newly adopted enzyme, NANOX one now delivers enhanced cleaning and deodorizing power.

(2) A clothing care formula that helps prevent yellowing, darkening, and dullness, while also protecting against color fading for longer-lasting wear.
NANOX one is the only*4 laundry detergent that combines highly-effective cleaning and deodorizing power with the ability to preserve the original colors of clothing. By pursuing detergency and deodorizing power while preventing color change, it contributes to extending the life of clothes.
*4 Among Lions laundry detergents

(3) Thorough antibacterial action,*5 virus removal,*6 and suppression of washing machine tub odors
Leaves clothing clean and pleasantly washed.
*5 Does not suppress the growth of all bacteria.
*6 Does not remove all viruses. Effect verified on one type of enveloped virus.

(4) Quick-rinsing formula, suitable for one-rinse washing
We recommend one-rinse washing out of consideration for the environment, contributing to saving water and energy as well as reducing CO2. Washing with a single rinse also reduces damage to clothing and helps prevent color change.

(5) Main bottle made with 100% recycled plastic (PET)
The main bottle is made of 100% recycled plastic (PET) derived from collected used plastic bottles and other materials.

5. Product lineup

Since its launch in 2010, the TOP NANOX brand has been loved by many customers. In 2023, it entered a new stage as NANOX one, and it has now evolved further with the addition of the new enzyme.

[Related information]
・Lion’s “Choose one Project”https://fabric.lion.co.jp/sustainability/chooseone/(Japanese only)
・ Lion takes up the challenge of promoting eco-friendly habits and announces the “Choose one Project,” launched on Earth Day, April 22, 2024:(Japanese only)

NANOX one brand website:
https://nanox.lion.co.jp/ (Japanese only)

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