Acne medicines
Acne medicines
PAIR® Acne Cream W

A topical medication that helps treat acne that has caused inflammation and redness
Product directions and other info
- Contents
- 14g; 24g
- Recommended retail price
- 14g: ¥950; 24g: ¥1,450
Indications
Pimples, acne
Directions and Dosage
Multiple times a day, wash the face with soap, then apply a thin layer to the affected area.
To break the seal on the tube
Invert the cap and press firmly
onto the mouth of the tube,
piercing the seal.
- (1)
- Use the product only on the area affected by pimples and acne; do not apply broadly to the surrounding area.
- (2)
- Avoid getting the product in the eyes. If the product gets in the eyes, wash immediately with warm or cold water. If irritation or other symptoms are severe, seek treatment from an ophthalmologist.
- (3)
- For administration to children under the supervision and guidance of a guardian or caretaker.
- (4)
- For external use only.
Ingredients
- Active ingredient
- Content
- Ibuprofen piconol (IPPN)
- 3.0%
- Isopropyl methylphenol (IPMP)
- 0.3%
*Inactive ingredients: Stearyl alcohol, polysorbate 60, disodium edetate, paraben, diisopropanolamine, octyldodecanol, 1,3-butylene glycol, carboxyvinyl polymer, flavoring
PAIR® Acne Liquid Treatment

A topical medication that softens hardened dead skin cells, helping to treat acne as soon as it begins to appear
- Contents
- 120ml
- Recommended retail price
- ¥1,480
PAIR® Acne Creamy Foam

A mild adult-use medicated acne-prevention face wash formulated to help maintain beautiful skin
- Contents
- 80g
- Recommended retail price
- ¥1,200
PAIR® Acne Clean Lotion

A mild adult-use medicated acne-prevention skin toner formulated to help maintain beautiful skin
- Contents
- 160ml
- Recommended retail price
- ¥1,500
PAIR® A Tablet

An oral tablet medicine for recurring acne and irritated skin, such as that triggered by a disruption of daily routines
Product directions and other info
- Contents
- 60 tablets; 120 tablets
- Recommended retail price
- 60 tablets: ¥1,440; 120 tablets: ¥2,700
Indications
Reduces the following symptoms: Acne, rough skin, dermatitis, skin irritation, chafed skin, eczema, canker sores, inflammation of the corners of the mouth, inflammation of the lips, inflammation of the tongue.
*Consult a doctor or pharmacist if these symptoms do not improve after using the product for about a month.
Replenishes vitamins B2 and B6 at times of physical exhaustion, during pregnancy or breastfeeding, or at times of reduced physical strength during or after illness
Directions and Dosage
Take the following amount with warm or cold water.
Age | Amount per 1 dose | Doses per day |
---|---|---|
Adults (15 years and up) | 1 tablet | 2 (morning and evening) |
Children under 15 years | × Do not use |
Usage and Dosage Warnings
Do not swallow the desiccants in the product's package.
Ingredients
Per 2 tablets (1 day's dose)
Active ingredient | Content | Purpose |
---|---|---|
Glucuronolactone | 200 mg | Supports the liver's functions of detoxifying and expelling unneeded substances in the body. |
Coix extract | 77 mg (equivalent to 1,001 mg crude drug) | An herbal medicine that helps improve acne and rough skin. |
L-cysteine | 30 mg | An amino acid that is a component of skin cells, is involved in energy metabolism and promotes the metabolism of the skin. |
Riboflavin (vitamin B2) | 30 mg | Supports the health of skin and other tissue, and regulates skin turnover. Also helps normalize sebum and protein metabolism. |
Pyridoxine hydrochloride (vitamin B6) | 100 mg |
*Inactive ingredients: Corn starch, hydroxypropylcellulose, cellulose, magnesium stearate, fumaric acid, stearic acid, polyvinylacetal diethylaminoacetate, hypromellose, titanium oxide, iron sesquioxide, macrogol
Note about ingredients
Using this product may cause urine to appear yellow. This is due to the vitamin B6 contained in the product that is absorbed by the body and excreted in urine, and is not cause for concern.
PAIR® Kanpo Extract Tablets

An herbal medicine that helps improve blood flow to treat premenstrual and other recurring pimples and blemishes
Product directions and other info
- Contents
- 112 tablets; 240 tablets
- Recommended retail price
- 112 tablets: ¥2,180; 240 tablets: ¥4,200
Indications
The following symptoms, for individuals who have adequate physical strength and sometimes suffer from lower abdominal pain, stiff shoulders, headache, heavy headedness, dizziness, or hot flashes with cold feet.
- ●
- Acne, eczema, dermatitis
- ●
- Blemishes
- ●
- Menstrual pain, irregular menstruation, menstrual abnormality, menopausal symptoms, female hormonal symptoms*
- ●
- Stiff shoulders
- ●
- Dizziness, heavy-headedness, bruising, chilblains
Warnings about indications
* Female hormonal symptoms: Physical and neuropsychiatric symptoms (including unstable mood or irritability) due to fluctuation in female hormone levels due to menstruation, pregnancy, childbirth, menopause, etc.
Directions and Dosage
Take the following amount before or between meals with warm or cold water.
Age | Amount per 1 dose | Doses per day |
---|---|---|
Adults (15 years and up) | 4 tablet | 2 |
Children under 15 years | × Do not use |
Usage and Dosage Warnings
Use only as directed.
Ingredients
8 PAIR® Kanpo Extract Tablets (1 day's dose) contain the following ingredients.
- Active ingredient
- Content
- Keishi-bukuryo-gan extract (2/3 volume)
(extract from 2.67 g each of cinnamomi cortex, poria sclerotium, moutan bark, peach kernel and peony root) - 1,533 mg
- Powdered cinnamomi cortex
- 100 mg
- Powdered poria sclerotium
- 100 mg
- Powdered moutan bark
- 100 mg
- Powdered peach kernel
- 100 mg
- Powdered peony root
- 100 mg
*Inactive ingredients: Cross-linked sodium CMC, silicon dioxide, talc, magnesium stearate, cellulose
Note about ingredients
Because this product is made with natural herbal medicines, tablets may vary somewhat in color, but these variations do not affect the product’s efficacy.
PAIR® A

A beverage-type treatment that is easy to quickly drink to treat recurring acne and irritated skin, such as that triggered by a disruption of daily routines
Product directions and other info
- Flavor
- Acerola
- Contents
- 50 ml (1 bottle)
- Recommended retail price
- 1 bottle: ¥260; 3 bottles: ¥780
Indications
Reduces the following symptoms: Acne, rough skin, inflammation of the corners of the mouth, inflammation of the lips, canker sores, inflammation of the tongue, eczema, dermatitis, skin irritation, chafed skin.
*Consult a doctor or pharmacist if these symptoms do not improve after using the product for about a month.
Replenishes vitamins B2 and B6 at times of physical exhaustion, during pregnancy or breastfeeding, or at times of reduced physical strength during or after illness
Directions and Dosage
Adults (15 years and up): Drink 1 bottle (50 ml) once a day.
Usage and Dosage Warnings
Use only as directed.
Ingredients
Per 1 bottle (50 ml)
- Vitamin B2 phosphate
- 38 mg
- Vitamin B6
- 100 mg
- Nicotinamide
- 60 mg
- Glucuronolactone
- 300 mg
- Coix extract
- 230.8 mg (equivalent to 3,000 mg crude drug)
Inactive ingredients: White soft sugar, fructose, erythritol, sodium benzoate, flavoring, ethanol, glycerin, vanillin, ethylvanillin, 2 other ingredients
Note about ingredients
The vitamin B2 in this product may cause urine to appear yellow, but this is not cause for concern.