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Interface Science

An interface is the boundary between any two of the three phases of matter (solid, liquid or gas); the study of such interfaces is interface science. For more than 100 years, Lion has been involved in interface science research, producing cutting-edge detergents and other products. In recent years, Lion has developed surfactants made from plant-derived palm oil, aiming to provide more environment-friendly products. The excellent detergency and biodegradability of these surfactants have garnered widespread attention. In addition, we employ world-leading technologies to study various interfacial mechanisms, such as those that produce foam, an interface phenomenon of air and liquid, and emulsions, an interface phenomenon of oil and water. By steadily advancing such research, we are expanding our focus from surfactants to include other areas as we work to develop the cleaning technologies of the future.

R&D Case Study

Research Accomplishment—Interface Technology

Interface Science

  • Novel Approach to Enhancing Skin Penetration of Active Ingredients by Cosmetic Film Formation on the Skin

    Annual Congress of SCCJ

    2025/12/10

    Sachiko Masaoka

  • Precipitation morphology and properties of surfactant-polymer complex formed by two cationic polymers

    3rd Annual Congress of the Society of Cosmetic Chemists of Japan

    2025/12/10

    Masayuki Nakagawa

  • Development of skin cleansing formulations that retain moisturizing agents on the skin

    Technical Education Publishing Online Seminar “Cleansing Technologies, Detergent Development, and Functional Innovation in Cosmetics and Toiletry Products 2025”

    2025/11/21

    Masayuki Nakagawa

  • Effect of phosphate in fluoride-calcium-phosphate complexes on fluoride retention in the oral cavity.

    The 47th Annual Meeting of Japanese Society tof Biomaterials

    2025/11/11

    Hikaru Takabayashi

  • Analysis of the Colloidal Gel Structure Formed by Aluminum Salts and Its Formation Mechanism

    Autumn Meeting 2025

    2025/10/28

    Sachiko Masaoka

  • Enhancing the Extrapolation and Interpretability of Stability Prediction Models for Body Washes: Application of Composition Descriptors and Modular Neural Network

    Journal of Computer Aided Chemistry

    2025/10/15

    Eisuke Inagaki

  • The 52nd Annual Meeting of the Society for Antibacterial and Antifungal Agents, Japan

    The Enhancing Effect of Branched Higher Alcohols on Viral Inactivation of Fatty Acid Salts

    2025/09/24

    Eijiro Murakami

  • Structural analysis of precipitated complexes (coacervates) of flexible-chain cationic polymer/surfactant mixtures

    The 76th Division Meeting of Division of Colloid and Surface Chemistry

    2025/09/22

    Sachiko Masaoka

  • Biomembrane permeation of non-steroidal anti-inflammatory drugs: Influence of molecular structure

    The 76th Division Meeting of Division of Colloid and Surface Chemistry

    2025/09/22

    Akira Sorada

  • Structural properties of double-chain cationic surfactant/higher alcohol mixed lamellar gel systems studied by small- and wide-angle X-ray scattering and electron microscopy

    The 76th Division Meeting of Division of Colloid and Surface Chemistry

    2025/09/22

    Masakazu Ono

  • Analysis of Surfactant Crystal Surface Structure in Organic Solvent-Containing Solutions Using 3D-SFM

    The 76th Division Meeting of Division of Colloid and Surface Chemistry

    2025/09/22

    Ryota Hashimoto

  • Surface Structure Analysis of Surfactant Crystals by the Addition of Organic Compounds Using 3D-SFM

    The 76th Divisional Meeting of Colloid and Surface Chemistry, Young Researcher Oral Presentation Award

    2025/09/22

    Ryota Hashomoto

  • Novel Approach to Enhancing Skin Penetration of Active Ingredients by Cosmetic Film Formation on the Skin

    iFSCC 35thCONGRESS

    2025/09/17

    Sachiko Masaoka

  • 35th International Federation of Societies of Cosmetic Chemists(IFSCC) in France 2025

    Demonstration of the efficacy of the moisturizing and itch-relief cream for sensitive skin that utilizes technology to increase the penetration of water-soluble active ingredients to the skin

    2025/09/17

    Meijia Li

  • Precipitation morphology and properties of surfactant-polymer complex formed by two cationic polymers

    35th International Federation of Societies of Cosmetic Chemists Congress

    2025/09/17

    Masayuki Nakagawa

  • Lipid membrane permeation of lipophilic substances through cholic salt micelles: Influence of molecular structure of lipophilic substances

    39th Conference of the European Colloid & Interface Society

    2025/09/09

    Akira Sorada (Joint research with Tokyo University of Science)

  • The Effect of Micelle Surface Charge Density on the Structural and Physical Property Changes of Soap/PDADMAC Adsorbed Complexes during the Rinsing Process

    The 63rd Annual Meeting of the Japan Oil Chemists' Society

    2025/09/03

    Shotaro Kariya

  • Lipid membrane permeation of lipophilic substances through cholic salt micelles: Influence of molecular structure of lipophilic substances

    The 63rd Annual Meeting of the Japan Oil Chemists' Society

    2025/09/03

    Akira Sorada (Joint research with Tokyo University of Science)

  • The 63rd Annual Meeting of the Japan Oil Chemists’ Society

    Enhancement of Viral Inactivation of Fatty Acid Salts by Branched Higher Alcohols and Mechanistic Analysis

    2025/09/03

    Wataru Shirae

  • Verification of Evaluation Methods for Persistence of the Antibacterial Effect after Handwashing with Hand Soap

    J.Soc.Cosmet.Chem.Jpn. Vol.59, No.2

    2025/05/31

    Masashi Tachikawa

  • Improving Extrapolation Performance and Interpretability of Multi-Component Compositions using Modular Neural Network

    The 47th Chemoinformatics meeting, 2025, Outstanding Poster Award

    2024/12/17

    Eisuke Inagaki

  • Structure and Solvent/ion Dynamics in Cationic Polymer/Anionic Surfactant Mixtures: Deeper Insights into Coacervation Phenomena

    International Symposium on Fiber Science and Technology 2024

    2024/11/27

    Sachiko Masaoka

  • Comparison of Surface Structures of Surfactant Crystals with Different Solubility by FM-AFM and MD Simulations

    32nd international Colloquium on Scanning Probe microscopy

    2024/11/18

    Ryota Hashimoto

  • Effect of Cholic Acid Salt and Its Mixed Micelles on the Morphology of Giant Unilamellar Vesicles (GUV)

    Journal of Oleo Science

    2024/10/28

    Miyuki Miyake

  • Molecular and Hydration Structure Analysis of MES-Na and MES-K Crystal Surfaces Using FM AFM and MD

    The 75th Civisional Meeting of Division of Colloid and Surface Chemistry

    2024/09/17

    Ryota Hashimoto

  • Structural analysis of precipitated complexes (coacervates) during the dilution process of cationic polymer/surfactant mixtures

    The 75th Civisional Meeting of Division of Colloid and Surface Chemistry

    2024/09/17

    Sachiko Masaoka

  • Molecular and Hydration Structure Analysis of MES-Na and MES-K Crystal Surfaces Using FM AFM and MD

    The 75th Civisional Meeting of Division of Colloid and Surface Chemistry

    2024/09/17

    Ryota Hashimoto

  • Membrane transport of lipid-soluble substances via bile salts: Effect of molecular structure

    75th Symposium on Colloid and Interface Chemistry

    2024/09/17

    Miyuki Miyake (Joint presentation with Tokyo University of Science)

  • Poster Award: Molecular and Hydration Structure Analysis of MES-Na and MES-K Crystal Surfaces Using FM AFM and MD

    75th Symposium on Colloid and Interface Chemistry

    2024/09/17

    Ryota Hashimoto

  • Poster Award: Membrane permeation of lipid-soluble substances via bile salts: Effect of molecular structure

    75th Symposium on Colloid and Interface Chemistry

    2024/09/17

    Miyuki Miyake (Joint presentation with Tokyo University of Science)

  • The diversity and fascinating nature of interface chemistry hidden in everyday items

    8th Young Researchers' Forum for Creating the Future of Colloid and Interface Chemistry Invited Lecture

    2024/09/16

    Astunori Morigaki

  • Friction Reduction Effect of Polymer Surfactant Complex on Clothing

    62nd Annual Meeting of Japan Oil Chemists Society

    2024/09/03

    Shinya Sudo

  • Structural analysis of organic-inorganic complexes that achieve both fluoride retention and sustained release

    62nd Annual Meeting of Japan Oil Chemists Society

    2024/09/03

    Hikaru Takabayashi

  • Effect of cationic group structure on the changes in properties of soap/cationic polymer complexes during rinsing

    62nd Annual Meeting of Japan Oil Chemists Society

    2024/09/03

    Kariya Syotaro

  • Persistence of the Antibacterial and Antiviral Effects after Skin Cleansing ~A New Approach to Suppress

    Journal of Oleo Science, Vol. 73, No. 7 (2024)

    2024/07/01

    Masashi Tachikawa

  • A study on foam formation in toilet spray detergent

    The 76th Annual Meeting of the Japan Society of Home Economics

    2024/05/26

    Chihiro Enodo

  • Texture and water absorption behavior of clothing treated with silicone fabric softener

    2024 AOCS Annual Meeting & Expo

    2024/05/01

    Hikaru Takabayashi

  • Ensuring the appearance quality of vitamin A eye drops

    27th General Drug Formulation Technology Seminar

    2024/03/09

    Shunsuke Uchino

  • Precipitation morphology and properties of surfactant-polymer complex formed by two cationic polymers.

    Oil Chemistry Seminar in 2020 - The forefront of oils and interfaces by young researchers

    2024/01/26

    Masayuki Nakagawa

  • Cacervate formetion mechanism and texture control

    Seminar sponsored by CMC Publishing

    2023/11/10

    Miyuki Miyake

  • Elucidation of the membrane permeation mechanism of lipid-soluble substances via bile salts - Study using phase-separated bilayer membranes -

    Japan Society of Colour Material

    2023/11/07

    Miyuki Miyake

  • Fractal structure analysis of thin film forming chlorohydroxyaluminum gel exhibiting antiperspirant function

    72nd Symposium on Macromolecules

    2023/09/26

    Sachiko Masaoka

  • Hierarchical structure of supramolecular fractal network gels comprising chlorohydroxyaluminum by USAXS/SAXS/WAXS experiments

    The 74th Divisional Meeting of Division of Colloid and Surface Chemistry

    2023/09/12

    Sachiko Masaoka

  • Japan Oil Chemists' Society Kanto Branch 11th (2023) Young Researcher Encouragement Award "Precipitation morphology and properties of surfactant-polymer complex formed by two types of cationic polymers"

    The11th (2023) Young Researchers Encouragement Award Japan Oil Chemists' Society Kanto Branch

    2023/09/08

    Masayuki Nakagawa

  • Analysis of the bactericidal action mechanism of alcohol-based solvents using giant unilamellar vesicles

    The 61st Annual Meeting of the Japan Oil Chemists' Society

    2023/09/07

    Yasuki Kato

  • Aggregate morphology and physical property changes during rinsing process of soap/PDADMAC composites

    The 61st Annual Meeting of the Japan Oil Chemists' Society

    2023/09/07

    Shotaro Kariya

  • Precipitation morphology and properties of surfactant-polymer complex formed by two types of cationic polymers

    The 61st Annual Meeting of the Japan Oil Chemists' Society

    2023/09/07

    Masayuki Nakagawa

  • Texture and water absorption behavior of clothing treated with silicone fabric softener

    The 61st Annual Meeting of the Japan Oil Chemists' Society

    2023/09/07

    Hikaru Takabayashi

  • The mechanism of bilayer permeation of oil-soluble substances with bile salt

    Formulation Conference 2023

    2023/07/03

    Miyuki Miyake

  • Acceleration of Toothpaste Dvelopment using Bayesian Optimization

    The 37th Annual Conference of the Japanese Society for Artificial Intelligence, 2023

    2023/06/09

    Eisuke Inagaki

  • 66th (2022) Oil and Fat Technology Paper Award "Synergistic effect of surfactant and chelating agent on stubborn keratin grime for easy cleaning"

    Oil & Fat Industry Kaikan Award

    2023/02/21

    Shinya Sudo

  • Fractal gel network structure comprising chlorohydroxyaluminum nanoparticles having antiperspirant function

    The 73rd Divisional Meeting of Division of Colloid and Surface Chemistry

    2022/9/20-9/22

    Sachiko Masaoka

  • 2021 (56th) Japan Oil Chemists' Journal of Oleo Science Editors’Award "Synergic Effects of Surfactant and Chelating Agent on Stubborn Keratin Grime for Easy Cleaning"

    J. Oleo Sci. 70, (12) 1769-1776 (2021)

    2021/11/9

    Shinya Sudo, Yosuke Watanabe, Kazuya Inomata, Ryo Hyodo, Atsushi Naito

    Research and Development Headquarters, Lion Corporation

  • 2021 (56th) Japan Oil Chemists' Society Industrial Technology Award "Developing a Method to Remove Stubborn Bathtub Keratin Grime and Application to the Bath Cleaner that can reduce the burden of daily cleaning"

    Oleo Science 2022 Volume22 Issue6 Pages 254-255

    2021/11/9

    Shinya Sudo, Ryo Hyodo, Yosuke Watanabe, Atsushi Naito

    Research and Development Headquarters, Lion Corporation

  • Structural Analysis of Nanoparticles and Gel Networks Formed by Chlorohydroxyaluminum by Small- and Wide-Angle X-ray Scattering

    The 72nd Divisional Meeting of Division of Colloid and Surface Chemistry

    2021/9/15-9/17

    Sachiko Masaoka

  • Enhancement of Virus Inactivation of Cationic Surfactants by Sulfate Ions

    The 60th Annual Meeting of the Japan Oil Chemists' Society

    2021/9/6-9/11

    Rei Saito

  • Dispersion stabilization of fragrance capsules in fabric softeners - Viscoelasticity control in vesicle systems based on depletion aggregation

    The 60th Annual Meeting of the Japan Oil Chemists' Society

    2021/9/6-9/11

    Asami Miyajima

  • Synergistic effects of surfactants and chelating agents on tightly adherent keratin for simple cleaning

    The 60th Annual Meeting of the Japan Oil Chemists' Society

    2021/9/6-9/11

    Shinya Sudo

  • Permeation Behavior of Liposoluble Substances Solubilized in Bile Salts/Phospholipid Mixture Micelles through Biological Membrane Models

    The 60th Annual Meeting of the Japan Oil Chemists' Society

    2021/9/6-9/11

    Sara Isurugi

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