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Body Care

Today, with the rapid changes in social and living environments, and the diversification of values and lifestyles, there is growing interest in maintaining health through self-care. To address the discomforts felt by each and every one of our consumers, we are developing a wide range of products that utilize life science and interface science, as well as bringing together our technological research capabilities cultivated through the development of fundamental technologies, to develop total health care products and services that enable individuals to practice self-care in order to maintain their health and well-being in a natural and positive way.

R&D Case Study

Research Accomplishment—Body Care

  • Foundation, Oil and Fat Industury Kaikan, 62th Excellent article award in Oil and Fat technology 「Membrane Permeation of Giant Unilamellar Vesicles and Corneal Epithelial Cells with Lipophilic Vitamin Nanoemulsions」

    Miyuki Miyake 1), Masatoshi Kurioka 1), Masahiro Takagi 2)

    1)Lion Corporation,2)Japan Advanced Institute of Science and Technology

  • Hair evaluation method based on the actual situation of consumers

    The 58th SOCIETY OF COSMETIC CHEMISTS OF JAPAN

    2022/2/8

    Izumi Oishi

  • Well-being as a Key Factor for the Creation of Sustainable Local Towns, People, and Workplaces: An Introduction to Well-being Management Initiatives in Ehime, a Region that Sees a Ray of Light in Solving Local Problems

    Wellbeing Expo & Conference ​2021 Autumn

    2021/11/4-11/5

    Takuya Ichinose

  • Approaches to Visualizing the Effectiveness of Care Focusing on Virus Contact Transmission in the Home

    Symposium on Cleaning

    2021/10/12-10/15

  • Development of materials and functional foods for dry mouth, eyes, and skin (dry syndrome)

    Food Development Expo 2021 (Hi Japan/ FiT Japan/ S-tec Japan/ LL Japan)

    2021/10/6-10/8

    Takao Iwai

  • Proper hand washing, gargling, and disinfection methods and their effects

    Division of Colloid Surface Chemistry

    2021/9/15-9/21

    Yuriko Omoto

  • Development of skin care detergents with excellent moisturizing and tactile properties

    Development and Latest Technology of Moisturizing Cosmetics for Prevention of Rough Skin and Hands

    2021/5/28

    Michihiro Suzuki

  • The visceral fat-reducing effect of enteric lactoferrin and its mechanism of action

    ifia/HFE JAPAN2021

    2021/5/12-5/14

    Tsubasa Yamaguchi

  • Washing Cosmetics

    Basic Cosmetic Technology Seminar

    2021/2/15-2/19

    Risako Toki

  • Foot trouble due to sweat and odor and development of corresponding products

    FRAGRANCE JOURNAL 2020 No.477(Vol.48/No.3)

    2021/3/15

    Shinichi Nagashima

  • Technology Introduction of "Nice Slim Essence Lactoferrin" to be delivered to the intestines ~~Visceral Fat Reduction Mechanism and Enteric Coating Technology~

    Japanese Association for lactferrin

    2020/12/6

    Takumi Mitsudome

  • Ideas for preventing infections in the home and workplace, hand washing and cleaning

    Japan Oil Chemicals' Society

    2020/11/2-11/7

    Yukari Sekine

  • Application of Anionic Polymers in Cosmetics

    COSMETIC STAGE Vol.15, No.1 2020

    2020/10/1

    Tomoki Sano

  • Intraoral Approach to Improve the Nasolabial Fold

    Cosmetic stage 14(6), 39-45, 2020-08

    2020/8/1

    Yujiro Endo

  • Washing the skin.

    Japanese Dermatological Association

    2020/6/4-6/7

    Hotaka Asano

  • The visceral fat-reducing effect of enteric lactoferrin and its mechanism of action

    ifia/HFE JAPAN 2020

    2020/4/20-4/22

    Takumi Mitsudome

  • Effect of lactoferrin intestinal solvent on visceral fat reduction

    Functional Food

    2020

    Michiaki Murakoshi、Kanae Nakamura、Tomoji Ono

  • Enteric-coated lactoferrin decreases abdominal visceral fat in humans: a randomized, double-blind, placebo-controlled, parallel-group study

    Jpn Pharmacol Ther 2020 : 48 : 1179-85

    2020

    Satoko Sato 1), Mitsuru Nomura 1), Akira Uchiyama 1), Ikuo Fukuhara 2)

    1)Research & Development Headquarters, Lion Corporation, 2) Fukuhara Clinic, Eniwa,

  • Effects of Coexistent Components on the Antiperspirant Action of Aluminium Chlorohydrate

    J. Soc. Cosmet. Chem. Jpn. 55(1): 45─51

    2020

    Tomoki Sano, Wataru Shirae, Yuriko Omoto, Shinichi Nagashima, Atsunori Morigaki, Yasushi Kakizawa, Takaki Ikenishi Research & Development Headquarters, Lion Corporation,

  • A Study on a Longitudinal Evaluation Method Using Facial Expression Analysis to Capture Emotional Changes during Cosmetics Use

    The Japanese Society for Cognitive Psychology

    Eisuke Inagaki

  • Rooibos extract, containing eriodictyol-6-C-β-D-glucoside as the active component, stimulate the M3 muscarinic acetylcholine receptor

    The 7th International Conference on Food Factors

    2019/12/1-12/5

    Takao Iwai

  • Influence of low-molecular-weight aggregates on aggregate growth kinetics and physical properties of solid-state proteins during storage

    Eur J Pharm Biopharm . 2020 Jan;146:10-18

    2019/11/16

    Takumi Mitsudome 1), Mitsutoshi Moribe 1),Yoshiyuki Obayashi 1), Akira Uchiyama 1),, Megumi Aono 1),

    1) Research & Development Headquarters, Lion Corporation,

  • Rooibos extract activates M3 muscarinic acetylcholine receptor and relieves human dryness

    The 29th Annual Meeting of the Japanese Society of Oral Medicine

    2019/9/20-9/23

    Takao Iwai

  • In vivo mechanism study on the dryness relief function of rooibos extract

    The 29th Annual Meeting of the Japanese Society of Oral Medicine

    2019/9/20-9/23

    Takao Iwai

  • Effects of Rooibos (Aspalathus linearis) Extract on Dryness of Mouth, Eye and Skin in Human

    The 28th Annual Meeting of the Japanese Society for Sjögren's syndrome

    2019/9/13-9/14

    Takao Iwai

  • Novel effects of rooibos extract on tear and saliva secretion mediated by the muscarinic acetylcholine receptor 3 in mice

    Journal of Oral Biosciences Volume 61, Issue 3, September 2019, Pages 179-182

    2019/8/7

    Rieko Arakaki 1), Aya Ushio 1), Satoru Kisoda 1), Mami Sato 1), Yoshitaka Nakamura 2), Kanako Yuyama 2), Riho Tateyama 2), Satoru Morishita 2), Noriyuki Monoi 2), Yasusei Kudo 1), Naozumi Ishimaru 3)

    1)Department of Oral Molecular Pathology Tokushima University Graduate School of Biomedical Sciences, 2)Research & Development Headquarters, Lion Corporation, 3) Department of Oral Molecular Pathology Tokushima University Graduate School of Biomedical Sciences,

  • Exercise and sports health claims in the system of Foods with Function Claims

    The 19th Scientific Meeting of the Japanese Society of Anti-Aging Medicine

    2019/6/14-6/16

    Mitsuru Nomura

  • Rooibos (Aspalathus linearis) extract, containing eriodictyol-6-C-β-D-glucoside as the active component, stimulates exocrine glands via the M 3 muscarinic acetylcholine receptor

    Journal of Functional Foods Volume 55, April 2019, Pages 248-254

    2019/2/7

    Saori Nishimachi a),Takao Iwai a), Yoshitaka Nakamura a), Kanako Yuyama-Masuda a), Takuya Tsutsui a),Noriyuki Monoi a), Akira Uchiyama a),b), Seiji Nakamura c),

    a)Research & Development Headquarters, Lion Corporation, b)Division of Oral Health, Growth, and Development, Faculty of Dental Science, Kyushu University, c)Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University,

  • A new in vitro muscle contraction model and its application for analysis of mTORC1 signaling in combination with contraction and beta-hydroxy-beta-methylbutyrate administration

    BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY 2019, VOL. 83, NO. 10, 1851–1857

    2019/01/04

    Satoko Sato 1), Mitsuru Nomura 1), Ikko Yamana 1), Akira Uchiyama 1), Yasuro Furuichi 2), Yasuko Manabe 2), Nobuharu L Fujii 2),

    1),Research and Development Headquarters, Lion Corporation, 2),Department of Health Promotion Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University ,

  • Relationship between female hormone and hair: Development of hair loss treatment

    Japan Hair Science Association

    2018/12/01

    Shunsuke Hiroshima

  • Quantitative Evaluation of Hair Growth in the Treatment of Hormone Replacement Therapy

    The Japan Society for Menopause and Women's Health

    2018/11/3-11/4

    Yujiro Endo

  • Effect of lactoferrin on energy expenditure enhancement in reprogrammed functional brown adipocytes

    25th International Conference of FFC

    2018/10/27-10/28

    Kanae Nakamura

  • Gene expression order attributed to genome reduction and the steady cellular state in Escherichia coli

    Front Microbiol. 2018; 9: 2255.

    2018/9/20

    Bei-Wen Ying 1),2), Kazuma Yama 3)

    1)Institute of Biology and Information Science, East China Normal University 2)Faculty of Life and Environmental Sciences, University of Tsukuba 3)Research & Development Headquarters, Lion Corporation

  • Gene expression order attributed to genome reduction and the steady cellular state in Escherichia coli

    Front Microbiol. 2018; 9: 2255.

    2018/9/20

    Bei-Wen Ying1),2), Kazuma Yama 3)

    1)Institute of Biology and Information Science, East China Normal University 2)Faculty of Life and Environmental Sciences, University of Tsukuba 3)Research & Development Headquarters, Lion Corporation

  • Design of multiscale structured composite particles through mechanical process for fabricating a powder layer with rapid drying properties

    SCEJ The Society of Chemical Engineers, Japan

    2018/9/18-9/20

    Koichiro Nakamura

  • Effects of lactoferrin on lipid metabolism in white adipocytes and brown adipocytes

    FOOD STYLE21

    2018/08/01

    Kanae Nakamura

  • Beta-hydroxy-beta-methylbutyrate (HMB) augments muscle contraction-induced protein synthesis via mTORC1 signaling in cultured L6 myotubes

    the european sleep research society

    2018/4/21-4/25

    Satoko Satoh

  • Establishment of a new in vitro exercise model and its application to analyze the mechanism of beta-hydroxy-beta-methylbutylate (HMB) on the contraction-induced protein synthesis

    the 2018 Annual Meeting of the Japan Society for Bioscience, Biotechnology and Agrochemistry

    2018/3/15-3/19

    Satoko Satoh

  • Relationship between female hormone and hair: Development of hair loss treatment

    Japan Hair Science Association

    2018/03/01

    Yujiro Endo

  • The sleep enhancement supplement Japanese sake yeast improves skin quality in humans—A randomized, double-blind placebo-controlled clinical trial—

    Japanese Pharmacology Therapeitics Volume 46, Issue 11, 1851 - 1857 (2018)

    2018

    Yuki Nagamori, et al.

  • Anti-Obesity Effect of Lactoferrin; Subgroup Analysis Excluding Subjects with Obese and/or Hyper-LDL Cholesterolemia

    Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry

    2018

    Tomoji Ono 1), Michiaki Murakoshi 1), Akira Uchiyama 1)

    1)Research & Development Headquarters, Lion Corporation

  • The effects of carotenoids intake for improvement of cognitive functions in healthy adults: a systematic review and meta-analysis of randomized controlled trials

    PROSPERO

    2018

    Takahiko Suiko

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