Lion takes its responsibility for providing customers with peace of mind through safety evaluations based on scientific evidence extremely seriously. We conduct wide-ranging safety assessments of the effects of Lion products and their raw materials on people and the environment, applying technologies related to living organisms, including those in the fields of molecular biology and physiology. These assessments ensure that customers can use Lion products with confidence. In addition to performing evaluations, Lion is involved in the development of safety assessment technologies, such as alternatives to animal testing.

The importance of safety evaluation and confirmation is the same worldwide. Lion takes a global perspective as it aggressively gathers and analyzes safety data from in and outside Japan and uses such data in actual safety evaluations. At the same time, Lion actively participates in various industry associations, cooperating to help solve problems.

R&D Case Study—Environment and human Safety

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  Developing Alternatives to Animal Testing and Drug Efficacy and Pharmacological Testing Methods

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  Evaluating Biodegradability and Environmental Impact—Fulfilling Our Social Responsibility to the Environment

External Presentation—Environment and human Safety

• The 32nd Annual Meeting of the Japanese Society for Alternatives to Animal Experiments (2019)

  Development of an Alternative Oral Mucosal Irritation Test Using a Three-dimensional Human Buccal Mucosal Model
  — Study on Setting of Oral Mucosal Irritation Evaluation Flow for Raw Materials and Products for Oral Care —

• The 32nd Annual Meeting of the Japanese Society for Alternatives to Animal Experiments (2019)

  Development of ADRA-OS (Amino acid Derivative Reactivity Assay-Organic Solvent reaction system) for poorly water-soluble sensitizers

• Journal of Applied Toxicology (2019)

  The within- and between-laboratory reproducibility and predictive capacity of the in chemico Amino acid Derivative Reactivity Assay (ADRA): Results of validation study implemented in four participating laboratories.

• Journal of Applied Toxicology (2019)

  The Cause of and Countermeasures for Oxidation of Cysteine-Derived Reagent Used in the Amino acid Derivative Reactivity Assay