Our Research: Product Development Research

Over-the-Counter Pharmaceuticals

As self-medication grows more common, consumers’ health-related needs are diversifying. In response, Lion is constantly working to develop highly functional products that leverage its proprietary technologies. This approach enables Lion to create products that have a unique market position. For example, Lion has used its proprietary technologies related to quickly dissolving active ingredients in the development of BUFFERIN analgesics and cold medicine. Lion’s technologies for the stable formulation of vitamin A have been used in Smile eye drops. Applying polymer technology, Lion created Halix topical analgesic and anti-inflammatory products, which are both gentle on the skin and highly adhesive. And Stoppa antidiarrheal products employ Lion’s oral medicine fast-disintegration technology, for relief whenever needed with just one tablet that can be taken without water. Going forward, Lion will continue to actively develop products based on its unique proprietary technologies.

R&D Case Study—Over-the-Counter Pharmaceuticals

External Presentation—Over-the-Counter Pharmaceuticals

  • 139th Annual Meeting of the Pharmaceutical Society of Japan(2019)

    The analgesic effect of aspirin on inflammatory pain rat is affected by administration timing and pain severity.

  • Life Science (2019)

    Mechanism of aspirin-induced inhibition on the secondary hyperalgesia in osteoarthritis model rats

  • PLOS ONE (2019)

    Nonsteroidal anti-inflammatory drugs and acetaminophen ameliorate muscular mechanical hyperalgesia developed after lengthening contractions via cyclooxygenase-2 independent mechanisms in rats

  • Journal of Oleo Science(2019)

    The Effect of Nonpolar Lipids in Meibum on Stability of Tear Film Lipid Layer against Compression-Expansion Cycles

  • Journal of Ocular Pharmacology and Therapeutics (2019)

    Effects of benzalkonium chloride and preservative-free composition on the corneal epithelium